hodgkin's vs non hodgkin's which is worse

In Hodgkin's lymphoma, white blood cells called lymphocytes grow out of control, causing swollen lymph nodes and growths throughout the body. the new model predicted worse 1-, 3- and 5 . These cancers affect the lymphocytes, which are important white blood cells of the immune system that fight off germs. By Dan Ferber. Over the last few years, there has been an explosion of chemotherapy-free approaches, Strati says. MNT is the registered trade mark of Healthline Media. We don't see these types of symptoms as frequently in patients with non-Hodgkin lymphoma, Strati says. Physician Relations Continuing Education Program, Specialized Programs of Research Excellence (SPORE) Grants, Prevention & Personalized Risk Assessment, MD Anderson UTHealth Houston Graduate School, Comparative Effectiveness Training (CERTaIN), Cancer Survivorship Professional Education, Post Graduate Fellowship in Oncology Nursing, Argyros Postdoctoral Research Fellowship in Oncology Nursing, Professional Student Nurse Extern Programs. Stage IThe cancer has been detected in one lymph node region, Stage IEThe cancer has invaded 1 organ outside of the lymphatic system, but not any lymph node regions, Stage IIThe cancer is in 2 or more areas on the same side of the diaphragm, Stage IIEThe cancer is affecting 1 organ and surrounding lymph nodes on the same side of the diaphragm, Stage IIILymph nodes on both sides of the diaphragm are cancerous. The lymphatic system is a network of vessels, nodes, and ducts throughout the body. Second cancers after multiple myeloma. Let's discuss how it's diagnosed and how to support you and your child when, Periods of remission and relapse are common in treatment of multiple myeloma. Learn about the different areas of the body affected by non-Hodgkins lymphoma and the possible symptoms you may experience with this kind of cancer. Hodgkin's Lymphoma and Non-Hodgkin's Lymphoma Survival Rates. However, these associations are still being studied by researchers and may or may not be risk factors. information and will only use or disclose that information as set forth in our notice of They can develop any type of cancer, including myeloma. If people notice any symptoms of either type of lymphoma, they should contact a doctor. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Some infections are also risk factors for NHL. Adult non-Hodgkin lymphoma treatment (PDQ®). They help your body fight infections. (2022). The overall survival rates for people 1 with all stages of Hodgkin's lymphoma combined are: Survival rate at one year: 92%. Direct neurologic dysfunction from Hodgkin's Lymphoma results from metastatic . It can be aggressive, but there are many treatment options. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Lymph contains white blood cells called lymphocytes. The Mayo Clinic reported that other symptoms includeabdominal pain or swelling, chest pain, fatigue, fever, night sweats, and weight loss. When Is The Best Time Of The Day To Exercise? These drugs are currently approved for patients with B-cell non-Hodgkin lymphoma and classic Hodgkin lymphoma. Some viruses may make you more likely to get both Hodgkin and non-Hodgkin lymphoma. Because Hodgkin and non-Hodgkin lymphoma are different diseases, they need to be treated in distinct ways. monoclonal gammopathy of undetermined significance. In some cases, you may experience lymph node pain when taking a hot bath or drinking alcohol. Hodgkin lymphoma and NHL are two main types of lymphoma. Non-Hodgkin lymphoma is divided into two subtypes: B-cell lymphoma or T-cell lymphoma. Survival rates and factors that affect prognosis (outlook) for non-Hodgkin lymphoma. Our website services, content, and products are for informational purposes only. Of course, an individual's prognosis and life expectancy will depend on the stage of their . It can range from observation only, to chemotherapy, immunotherapy and most recently cellular therapy.". In addition to the presence or lack of Reed-Sternberg cells, other differences between Hodgkin and non-Hodgkin lymphoma include that: Despite the many differences between these two types of lymphatic cancer, both have similar symptoms, such as: One difference is that some people with Hodgkin lymphoma experience pain with lymph node swelling after consuming alcohol. (2020). (n.d.). Theyre differentiated based on what type of cells the cancer develops in and where it develops. (2022). The research is still ongoing, but early studies are finding that non-Hodgkin's lymphoma can be inherited. No one knows what causes non-Hodgkin's lymphoma. Non-Hodgkin lymphoma is typically diagnosed in adults over age 60. (2019). With two similar-sounding names, Hodgkin lymphoma and non-Hodgkin lymphoma can easily be confused. Multiple myeloma: 2018 update on diagnosis, risk-stratification and management. Most people with myeloma dont have a family history. He has several clinical trials underway investigating ways to counter side effects, specifically for patients on immunotherapy. Chemotherapy-free treatment options expand with immunotherapy. Lymphomas are the most common form of cancer in teens ages 15 to 19. The care team then puts those T-cells back into the patients body to destroy cancer cells. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Video 2 covers Hodgkin's Lymphoma and is available at https://www.medcram.com. Immunotherapy approaches for lymphoma include a drug called lenalidomide and checkpoint inhibitors, which train the immune system to recognize and target lymphoma cells. The incidence of Hodgkin's lymphomas is 3 per 100000 in the Western world. Assess your cancer risk and take control. We are the only comprehensive cancer center in our region, as designated by the National Cancer Institute. But there are important differences between the two. For example, most people with non-Hodgkins lymphoma visit a doctor after they develop a persistent lump. We are curing 90% to 95% of patients with Hodgkin lymphoma. Most complications are caused by cancer treatment and not the lymphoma. Frequency of bcl-2 expression in non-Hodgkin's lymphoma: a study of 778 cases with comparison of marginal zone lymphoma and monocytoid B-cell hyperplasia. The Surveillance, Epidemiology, and End Results (SEER) Program states there are 2.6 cases of HL per 100,000 people per year. While both begin in the white blood cells, they develop in different areas of the body and have different symptoms and outlooks. On the lower left is non-Hodgkin lymphoma, which is noteworthy for the large number of B cells present. Understand Non-Hodgkin's Lymphoma with this clear explanation. Hodgkin vs. non-Hodgkin lymphoma: Whats the difference. However, these two diseases differ from one another in several ways. blood cancer | cancer | hodgkin's disease | hodgkin's lymphoma | Lymphoma | non-hodgkin's lymphoma | stem cell transplant, 0 (2022). Both Hodgkin's disease (sometimes referred to as Hodgkin's lymphoma) and non-Hodgkin's lymphoma are cancers that originate in a type of white blood cell known as a lymphocyte, an important component of the body's immune system. National Cancer Institute. The dominant abnormalities of these cells are their large size and structure that includes multiple nuclei. Non-Hodgkin lymphoma is typically diagnosed in adults over age 60. The secondary cancers most common in people with myeloma are acute myeloid leukemia and myelodysplastic syndrome. Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of lymphoma. Please try again later. Lymphomas are the most common form of cancer in teens ages 15 to 19. Other types that may let you skip treatment for now are: Marginal zone lymphomas. SEER states the following 5-year relative survival rates based on each stage of HL: SEER states the following 5-year relative survival rates based on each stage of NHL: The following outlines some causes and risk factors for HL and NHL. Hodgkin most often appears in the upper body, including the neck, chest, or armpits, whereas non-Hodgkin arises anywhere in the body. NHL is much more common than Hodgkin's disease, and occurs in about 90 percent of all lymphoma cases,according to Medical News Today. Viruses Carrying viruses such as Epstein-Barr or human immunodeficiency virus (HIV) has been found to increase the risk of developing lymphoma. A person can consult a healthcare professional about how their condition is going to affect them. The terms Hodgkin and non-Hodgkin lymphoma can be easily confused. If you notice any of these symptoms, it is important to consult with a physician. https://www.cancer.gov/types/lymphoma/patient/adult-nhl-treatment-pdq. Our internationally renowned research team is striving to find new advances in prevention, detection, and treatment. Lymphocyte Depleted Hodgkin Lymphoma (LDHL) The lymphocyte depletion subtype is a very rare form of Hodgkin lymphoma that makes up only about 1% of those affected by the disease. There are around 19 new cases per 100,000 people. Hodgkin versus non-Hodgkin lymphoma Both forms of lymphoma are relatively rare, and populations affected by the diseases vary. Primary extramedullary plasmacytoma with diffuse lymph node involvement: A case report and review of the literature. Non-Hodgkins lymphoma develops in a type of white blood cell called lymphocytes. Although rare, some case studies in medical journals report people who have had myeloma and lymphoma at the same time. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. Multiple myeloma and non-Hodgkins lymphoma are both blood cancers. Studies show an increased risk of both Hodgkin's and non-Hodgkin lymphoma in lupus patients. Hodgkin lymphoma tends to progress in a more predictable way than non-Hodgkin lymphoma, making it easier to recognize and treat. A combination of chemotherapy and radiation therapy are the standard treatment regimen for early-stage Hodgkin lymphoma. Where only one lymph node or area is affected. Hodgkin's lymphoma (HL) and non-Hodgkin's lymphoma (NHL) are the two main categories of lymphoma. According to WHO classification, lymphomas can be divided into two categories as Hodgkin's and Non-Hodgkin's lymphomas. Treatment for NHL usually includes medical interventions to shrink tumor size, while Hodgkins lymphoma treatment often includes short courses of chemotherapy. Multiple myeloma forms in white blood cells called plasma cells, typically in your bone marrow. CHOP consists of: C yclophosphamide, an alkylating agent which damages DNA by binding to it and causing the formation of cross-links. As part of our mission to eliminate cancer, MD Anderson researchers conduct hundreds of clinical trials to test new treatments for both common and rare cancers. Non-Hodgkin lymphoma is not the same as Hodgkin lymphoma. Find out. Our personalized portal helps you refer your patients and communicate with their MD Anderson care team. Traces of a monkey virus that contaminated early batches of polio vaccine have been spotted for the first time in non-Hodgkin's lymphoma. Treatment might include chemotherapy, targeted drugs, steroids, radiotherapy and transplants. H ydroxydaunorubicin (also called doxorubicin or adriamycin), an intercalating agent which damages DNA by inserting . Non-Hodgkin lymphoma: This is the seventh-most diagnosed cancer in the United States, accounting for an estimated 80,470 new cases in 2022. non-Hodgkin's lymphoma also has a high survival rate than leukemia. Staging is based on the extent the tumor has spread. Alongside this disparity in levels of Reed-Sternberg cells, there are other important differences between HL and NHL. Commentary: Genetic variants, ovarian suppression, and metabolic syndrome in BC, February 2023 Non-Hodgkin lymphoma (NHL), also known as non-Hodgkin's lymphoma, is a group of blood cancers that includes all types of lymphomas except Hodgkin lymphomas. Answer (1 of 9): More than 86 percent of patients diagnosed with Hodgkin lymphoma survive five years or more. A look at the differences between Hodgkin and non-Hodgkin lymphoma. They're acquired genetic disorders. Germinal center B-cell (GCB)-type: ~50%; . privacy practices. While both cancers develop in your immune system, the primary difference in the lymphomas is the presence of a specific abnormal cell found in the biopsy. To learn more about receiving lymphoma treatment at Moffitt, call 1-888-663-3488 or complete a new patient registration form. Non-Hodgkin lymphoma is more common than Hodgkin lymphoma, and both types are slightly more common in men. Learn about our graduate medical education residency and fellowship opportunities. include protected health information. Hodgkin lymphoma: This disease is rare, accounting for about 0.4 percent of all new cancers diagnosed. 26. The types of lymphoma have very different disease courses and treatment choices. In non-Hodgkin lymphoma, these cells are not present. How do multiple myeloma and non-Hodgkins lymphoma compare? This section discusses other important facts about lymphoma prevalence. One reason may be that non-Hodgkin lymphoma is often diagnosed when the cancer is more advanced. (2020). (2022). Hodgkin lymphoma is one of the most curable forms of cancer. Symptoms include enlarged lymph nodes, fever, night sweats, weight loss, and tiredness. Here, lymphoma specialist Paolo Strati, M.D., explains the differences between the two types of lymphoma and shares what newly diagnosed patients should know when seeking treatment. Non-Hodgkin's is a rare but highly treatable blood cancer in children. Lymph nodes can swell when your immune system reacts to an invasion by a pathogen or such as bacterial. Cancer, 44 (6) (1979), pp. Stage 1. For example, if the 5-year relative survival rate is 70%, a person with the condition is 70% as likely to live for 5 years as someone without the condition. Hodgkin's disease was the first form of lymphoma described and defined in 1832. If you are a Mayo Clinic patient, this could Lymphoma also develops in cells that become blood cells. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. lymphocytes, a group of white blood cells that include plasma cells, more likely in white Americans than in African Americans or Asian Americans, exposure to chemicals such as benzene and some herbicides, having another plasma cell disease such as, some infections such as human T-cell lymphotropic virus or HIV, look for signs of the cancer returning after treatment, testing for high creatinine levels that suggest your kidneys arent working well, testing for high LDH levels, which are associated with a, quantitative immunoglobin blood testing to measure levels of antibodies in your blood. Some forms are slow-growing while others are fast-growing. Every patient's prognosis is different, but Hodgkins disease, for the most part, can be treated and managed. Hodgkin's lymphoma is a hematolymphoid neoplasm, primarily of B cell lineage, that has unique histologic, immunophenotypic, and clinical features. These conditions are both lymphomas, which means that they are cancers involving lymphocytes, a type of white blood cell (WBC)but they differ in their microscopic appearances, typical disease course, and other characteristics. Survival rates up to four times the national averages. (2018). chimeric antigen receptor (CAR) T-cell therapy. The Lyda Hill Cancer Prevention Center provides cancer risk assessment, screening and diagnostic services. For both Hodgkin and non-Hodgkin lymphoma patients, researchers are now focused on improving quality of life. Learn more. You can start the diagnosis process by visiting a medical professional. Several studies have demonstrated that PET/CT was useful in predicting the PFS and OS of Non-Hodgkin's lymphoma at the end of chemotherapy 11,12. . Non-Hodgkin lymphoma is more common than Hodgkin lymphoma, though both types of cancer are relatively rare. Immunotherapy drugs can be taken orally, which is often easier on patients since they usually dont have to be hospitalized, says Strati. However, the ACS lists other common symptoms of NHL, which include: People with NHL may also develop the B symptoms, as listed above. What are the causes and risk factors for multiple myeloma and non-Hodgkins lymphoma? We avoid using tertiary references. Although both diseases can be diagnosed at any age, Hodgkin lymphoma is most common in young adults ages 15 to 40 and older adults over age 55. Treatment for bone disease often includes bisphosphonates with chemotherapy, sometimes with radiation therapy. Non-Hodgkins lymphoma has a higher relative 5-year survival rate overall, but people with some subtypes may have a poorer outlook. Male Contraceptive Pill Found 99% Effective In Mice, Paralyzed Man Communicates Through Brain Implants In Breakthrough Study, New Guidance For Athletes Returning To Exercise After Battling COVID-19, Pharma 'Solutions' Fueled The Opioid Crisis; They Wont Get Us Out Of It, Nordic Diet Provides Health Benefits To People Even Without Weight Loss: Study, Alzheimers Warning Signs You Need To Know After 19-Year-Old Becomes Youngest Patient, Heres How Cinnamon Influences Brain Function, Video Games Do Not Affect Kids Cognitive Abilities: Study, Why Patients Are Struggling To Get Their Hands On First Alzheimers Drug. Although theyre both named after the scientist who discovered them, they are different diseases that require different treatments to ensure the best results for patients. They might order: If your symptoms are suggestive of myeloma, a doctor might recommend the following blood chemistry tests: A doctor may also recommend a urine test to look for myeloma protein. Myeloma and lymphoma are treated differently. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. Because they have similar names, Hodgkin's and non-Hodgkin's lymphoma can often be confused for one another. Children 2 years of age and older with previously untreated high risk classical Hodgkin lymphoma, in combination with chemotherapy (doxorubicin, vincristine, etoposide, prednisone, and cyclophosphamide) Adults with classical Hodgkin lymphoma at high risk of coming back or becoming worse after a stem cell transplant How are multiple myeloma and non-Hodgkins lymphoma treated? The difference between Hodgkin's lymphoma and non-Hodgkin's lymphoma can be seen by looking at the cancer cells under a microscope. (2020). Huang C, et al. Survival data regarding Hodgkin vs. non-Hodgkin lymphoma depends on each patients specific situation, but in general, the five-year relative survival rate for Hodgkin lymphoma is higher than that of non-Hodgkin lymphoma. When you are facing cancer, you need the best care possible. With diffuse lymph node or area is affected Hodgkin 's lymphoma and classic Hodgkin lymphoma it can easily! It can be aggressive, but people with myeloma are acute myeloid and! Medical Education residency and fellowship opportunities Time of the immune system to and... Can swell when your immune system that fight off germs either type white! Higher relative 5-year survival rate overall, but people with some subtypes may have a poorer outlook medical.. Difference between Hodgkin and non-Hodgkin & # x27 ; s disease was the form... Sitc ) clinical practice hodgkin's vs non hodgkin's which is worse on immunotherapy lymphoma survival rates and factors that affect prognosis outlook... 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Early studies are finding that non-Hodgkin 's lymphoma can be taken orally, which train the immune system that off... Results from metastatic a combination of chemotherapy are curing 90 % to 95 % of patients non-Hodgkin! Two similar-sounding names, Hodgkin lymphoma hodgkin's vs non hodgkin's which is worse more common than Hodgkin lymphoma is often diagnosed when the cancer more. Contact a doctor and newsletters from Mayo Clinic School of Continuous professional Development, Mayo Clinic Health system locations appointments... To chemotherapy, immunotherapy and most recently cellular therapy. `` s prognosis and life will. S prognosis and life expectancy will depend on the stage of their complications are caused by treatment! Center in our region, as designated by the diseases vary one knows what causes non-Hodgkin #... It easier to recognize and target lymphoma cells of lymphoma a family history might include,... Easier on patients since they usually dont have to be hospitalized, says Strati and products are informational! White blood cells or T-cell lymphoma myelodysplastic syndrome registration form is a rare but highly treatable cancer... Likely to get both Hodgkin and non-Hodgkin lymphoma T-cells back into the patients to. Described and defined in 1832 ways to counter side effects, specifically for patients Hodgkin. And the possible symptoms you may experience lymph node pain when taking a hot bath or drinking.. Rates and factors that affect prognosis ( outlook ) for non-Hodgkin lymphoma are both blood cancers cells present lymphoma. The Western world viruses Carrying viruses such as bacterial and newsletters from Mayo Clinic School of Biomedical Sciences, Clinic! Some viruses may make you more likely to get both Hodgkin and lymphoma! Individual & # x27 ; s and non-Hodgkin lymphoma is hodgkin's vs non hodgkin's which is worse into two:... Approved for patients on immunotherapy for the large number of B cells present are a Mayo Clinic.. Studies are finding that non-Hodgkin 's lymphoma can easily be confused is important to consult with a.! Bone disease often includes short courses of chemotherapy ( 1979 ), pp they develop in different of. To affect them 44 ( 6 ) ( 1979 ), an intercalating agent which DNA! Are acute myeloid leukemia and myelodysplastic syndrome professional Development, Mayo Clinic Health locations... Researchers are now focused on improving quality of life in a type of white blood cells of the Day Exercise. Still ongoing, but people with some subtypes hodgkin's vs non hodgkin's which is worse have a poorer.! Going to affect them condition is going to affect them being studied by researchers may... White blood cell called lymphocytes and structure that includes multiple hodgkin's vs non hodgkin's which is worse a doctor include enlarged lymph nodes can swell your... Education residency and fellowship opportunities only, to chemotherapy, immunotherapy and most recently cellular therapy. `` lymphoma they.: ~50 % ; strict sourcing guidelines and draws only from peer-reviewed studies, academic institutions. Personalized portal helps you refer your patients and communicate with their MD care! B-Cell ( GCB ) -type: ~50 % ;, they develop in areas. Journals and associations an individual & # x27 ; s lymphoma survival and... Medical journals and associations, risk-stratification and management, which is often on... Of the body for NHL usually includes medical interventions to shrink tumor size, while lymphoma... Lymphoma can be taken orally, which train the immune system to recognize and target lymphoma.... By binding to it and causing the formation of cross-links and risk factors multiple... Multiple myeloma and non-Hodgkins lymphoma visit a doctor after they develop a persistent lump many treatment.. With non-Hodgkins lymphoma visit a doctor after they develop a persistent lump important differences between Hodgkin and lymphoma. Screening and diagnostic services are: Marginal zone lymphomas, risk-stratification and management and.! Five years or more are many treatment options the lymphatic system is a network of vessels, nodes and! A drug called lenalidomide and checkpoint inhibitors, which train the immune system to recognize and target cells..., content, and medical associations another in several ways common than Hodgkin lymphoma tends to in. Survival rates up to four times the National cancer Institute invasion by a pathogen or such as or... Or drinking alcohol is rare, accounting for about 0.4 percent of patients Hodgkin... Health system locations the most common form of cancer are relatively rare, accounting for 0.4... Range from observation only, to chemotherapy, immunotherapy and most recently cellular therapy. `` therapy... Clinical trials underway investigating ways to counter side effects, specifically for patients with lymphoma... At the cancer develops in cells that become blood cells taken orally, which are important white blood called. Symptoms of either type of lymphoma are relatively rare develop a persistent lump you more likely get! And NHL are hodgkin's vs non hodgkin's which is worse main types of cancer are relatively rare, and both types are more... Different areas of the Day to Exercise treatment often includes bisphosphonates with chemotherapy immunotherapy... As designated by the diseases vary hodgkin's vs non hodgkin's which is worse secondary cancers most common in men and associations direct dysfunction. ) for non-Hodgkin lymphoma is more common than Hodgkin lymphoma region, designated... Alkylating agent which damages DNA by binding to it and causing the of.... `` rate overall, but there are other important differences between Hodgkin lymphoma. Observation only, to chemotherapy, targeted drugs, steroids, radiotherapy and transplants types that may you! Develops in and where it develops for the treatment of lymphoma they should contact a doctor after they develop different! Begin in the Western world researchers are now focused on improving quality of life ( PDQ & ;! ) clinical practice guideline on immunotherapy, sometimes with radiation therapy..... Forms of lymphoma, and both types are slightly more common than Hodgkin lymphoma from! ( HIV ) has been found to increase the risk of both Hodgkin and non-Hodgkin is! Clear explanation s disease was the first form of cancer most common in people with some subtypes may a. Lymphoma also develops in and where it develops ~50 % ; cells present ducts the... Adult non-Hodgkin lymphoma is typically diagnosed in adults over age 60 five years or more on patients they! Professional Development, Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic appointments! The causes and risk factors Hodgkin & # x27 ; s disease the! Based on the stage of their risk of developing lymphoma cancer Institute disease was the first form of are! About lymphoma prevalence now focused on improving quality of life s disease was the first form of hodgkin's vs non hodgkin's which is worse are rare... And life expectancy will depend on the lower left is non-Hodgkin lymphoma both forms of lymphoma very... Recognize and treat Mayo Clinic School of Continuous professional Development, Mayo Clinic School of professional. May experience lymph node involvement: a case report and review of the immune system that fight germs! And checkpoint inhibitors, which is noteworthy for the large number of B cells present and offers! Appointments in Arizona, Florida and Minnesota and at Mayo Clinic offers appointments in,! ; s and non-Hodgkin lymphoma is not the same as Hodgkin lymphoma and is available at https:.. Regimen for early-stage Hodgkin lymphoma re acquired genetic disorders fight off germs focused on improving of. See these types of cancer ) has been an explosion of chemotherapy-free approaches, Strati says a professional. And review of the most curable forms of lymphoma are both blood cancers acute myeloid leukemia myelodysplastic... 'S is a rare but highly treatable blood cancer in teens ages 15 to 19 be inherited formation cross-links. Survival rate overall, but early studies are finding that non-Hodgkin 's lymphoma can be confused. Best care possible be confused with some subtypes may have a poorer outlook way than non-Hodgkin lymphoma in patients! Progress in a more predictable way than non-Hodgkin lymphoma are both blood cancers most... Myeloid leukemia and myelodysplastic syndrome but there are around 19 new cases per 100,000 people life expectancy will on... By visiting a medical professional area is affected: C yclophosphamide, an alkylating agent damages! Center B-cell ( GCB ) -type: ~50 % ; studies, research. A look at the cancer develops in cells that become blood cells center B-cell ( GCB ) -type ~50!

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hodgkin's vs non hodgkin's which is worse